The downside is that I'm not really sure Vertex wants to get into the CAR-T business, which is basically the other half of CRISPR's clinical pipeline. If there's anything we've missed, or any additional information you'd like to see, please reach out and let us know. But Alnylam's study isn't the only major readout expected this year for a genetic heart condition that's become a top target for many drugmakers. Dealmaking is essential to the business of drug development. Ionis (NASDAQ:IONS) is commercial-stage biopharma developing RNA-targeted therapy using antisense technology that can control gene expression in a cell using antisense oligonucleotides (ASO). I own Vertex so I certainly don't want Vertex overpaying for CRISPR Therapeutics. They are my opinions only. Markets. Therefore, I am picking 5 best Mid-cap biotech acquisition targets in this post with deal value less than $10B each. Are you interested in learning more about small- and mid-cap biotech stocks with exceptional growth potential and some of the hottest takeover targets of the industry? If you have an ad-blocker enabled you may be blocked from proceeding. The acquisition will provide Sanofi access to Amunix Pro-XTEN, XPAT and XPACT technology, complementing Sanofis existing R&D platforms. 9. Therefore, leading companies such as CRISPR Therapeutics, Intellia Therapeutics, or Editas Medicine might catch the eye of large pharmaceutical companies trying to step into this field and complement their pipeline with CRISPR/Cas9 technology. BMRN briefly touched $100.13 on February 5, 2019. Aesther Healthcare Acquisition Corp (NASDAQ: AEHA) Announces Filing of Definitive Proxy Statement with SEC in Connection with its Proposed Business Combination with Ocean Biomedical, Inc. Capsa Healthcare Acquires Tryten Technologies to Strengthen Its Leadership Position in Mobile Computing. Go and get our Biotech Investments HOT STOCK REPORT. Gilead Sciences (GILD -1.00%) also has not been shy about making smaller deals. Only one year later, the company was granted FDA approval for Myfembree (relugolix) in combination with two hormone drugs as the first once-daily treatment for heavy menstrual bleeding linked to uterine fibroids in premenopausal women, with a treatment duration for up to two years. Youre reading a free article with opinions that may differ from The Motley Fools Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Just briefly, very quickly, I think Biogen (BIIB 0.54%) needs to make an acquisition -- ticker for Biogen is BIIB. Alnylam was founded in 2002 as a spin-off from the Max Planck Institute for Biophysical Chemistry in Gttingen, Germany. Create your Watchlist to save your favorite quotes on Nasdaq.com. To make the world smarter, happier, and richer. The company has a team of world-class researchers, trying to transform the company-owned CRISPR/Cas9 gene-editing platform into breakthrough human therapeutics. Premiums were calculated using the acquired company's share price at the previous trading day's close, Only one therapeutic category is counted for each acquired company. Which company is going to get bought? The Motley Fool recommends Biogen and Gilead Sciences. In September, the rumor mill kept its employees working overtime by reporting that international pharmaceutical juggeraut Roche ( RHHBY -1.10%) was trying to arrange $15 billion in financing to. Luke Lango will reveal how you could start collecting cash payouts like $4,600 in 48 days or $12,000 in 21 days, without touching risky options or any other confusing investments. Trading stocks is risky -- always be sure to know and understand your risk tolerance. Example: +water -Europe The successful development and commercialization will significantly boost ADAP and make it an attractive buyout candidate. Antares Pharma ( ATRS ) We first began to hear acquisition rumors in Antares in late 2011. Sold Tercica to Ipsen: Mr. King served as President and General Manager of Tercica. Analysts, on average, predict over 75% upside for Crispr shares. We believe there is merit to the current rumors surrounding AcelRx. After a lengthy drought, could biotech M&A be on the upswing? To help, we've provided a guide detailing how to prepare if your company is being acquired. Well, first, I am a shareholder of both Vertex and Bristol-Myers Squibb, so I like your ideas there. Rumors again surfaced in 2016 that Roche would acquire BioMarin in a deal that could be in the range of $130 to $150 per share. It could find some synergies in having salespeople sell just the same set of drugs from both companies. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services. quotes delayed at least 15 minutes, all others at least 20 minutes. Outsmart the market with Smart Portfolio analytical tools powered by TipRanks. The company has already seven products on the market. Additionally, it has a robust gene therapy pipeline, targeting DMD, limb-girdle muscular dystrophies and several other indications. Lynparza is co-developed by AstraZeneca and Merck, while Zejula, which is from the stable of Tesaro, is now under the aegis of GlaxoSmithKline, following the former's acquisition by the British drugmaker. Who will buy? Given that the FDA is yet to approve a NASH drug, it is worth taking a risk with this one-trick pony. Nevertheless, as the economic situation improves, the pace is picking up, and bigwigs like Gilead, Bristol Myers, Novartis are evidently on the lookout to bolster their portfolios. The companies are already partners for CRISPR's beta-thalassemia and sickle cell therapy. Hunzinger said: Biotech and smaller medical device deals should continue in the first half of the year, with the second half poised for larger deals driven by a need for scale and an expected settling of the regulatory landscape.. Speights: Now, Brian, I'm going to agree with you on every point you just made. (Source: EY 2019 M&A Firepower Report) 1. They could develop that in combination. While 2022 started rather quiet as it pertains to M&A, the second quarter was one of the busiest three-month periods for acquisitions in recent years. The company is also developing CRISPR gene-editing therapeutic candidates for DMD. I think those could be intriguing deals for the new year. Over the last few years, pharmaceutical M&A hit record highs as larger companies turned again and again to young biotechs for innovation. In the 3rd quarter call, Jack Howarth stated that Antares approached Pfizer looking to collaborate with them. Acquisition rumors have swirled around specialty biotech BioMarin Pharmaceutical (NASDAQ: BMRN) for years now.In fact, Genetic Engineering & Biotechnology News has had it on its takeover target . 5 min read Mergers & acquisitions (M&A) are back in focus in the biotech sector after a tepid run in the last couple of years. FTX Fooled the World. The Food and Drug administration (FDA) approved its fourth RNAi therapeutic product Leqvio in December 2021 for lowering LDL-cholesterol, aka bad cholesterol. Scott is an independent investor/writer/trader and team leader of StockMatusow.com. Below we discuss companies that have promising drugs/candidates in the pipeline and could be potential takeover targets: BioMarin BMRN has been on the takeover radar for quite some time now. Management consulting firm Ernst & Young, meanwhile, believes biopharma companies will be under pressure to use M&A and partnerships to mitigate the impact of patent cliffs and to foray into new modalities of therapeutic options. If approved, ValRox will be available for patients well in advance of Pfizer and Sangamo Therapeutics gene therapy Giroctocogene Fitelparvovec, for which the two companies voluntarily paused the phase 3 clinical trial program last year for changes to the protocol. "Human natural killer cell" [Micrograph]. 2019 saw more than 25 acquisition deals executed in the biotech sector, of which 14 were billion-dollar deals. Calyxt, Inc. (Nasdaq: CLXT), a plant-based synthetic biology company, and Cibus, a leader in precision gene editing in agriculture, today announced that both companies have entered into a definitive merger agreement under which Calyxt and Cibus will merge in an all-stock transaction. In 2021, more than a dozen biotech companies have been snapped by big pharmaceutical companies. Making the world smarter, happier, and richer. Earlier, Merck acquired erstwhile Acceleron Pharma for $180 per share in cash for an approximate total equity value of $11.5 billion to build its rare diseases portfolio. While Some Have Learned From It, Others Wont. Below you can find the official Biotech Investments M&A and takeover list containing some of the hottest takeover targets in biotech industry for H2 2022. Acelrx's Nanotab tech could potentially grab a significant piece of this market. Go and get our, Eckert & Ziegler Strahlen- und Medizintechnik AG. The Company submitted a Marketing Authorization Application to the. According to Glenn Hunzinger, U.S. Pharmaceutical & Life Sciences Consulting Solutions Leader at PricewaterhouseCoopers. In early 2017, the rumor mill was spinning with whispers of Gilead (GILD) close to acquiring Incyte. Capsa Healthcare, a leading innovator in healthcare delivery solutions for hospitals, long-term care, and retail pharmacy providers, announced the acquisition of Tryten Technologies Inc., a designer and manufacturer of lightweight, easy to maneuver mobile cart solutions. 10 stocks we like better than Vertex PharmaceuticalsWhen our award-winning analyst team has a stock tip, it can pay to listen. A Roth Capital Partners analyst remarked in May of this year that he believes ACAD is on big pharmas' radar as an acquisition target. Ra Medical Systems (NYSE American: RMED) announces a realignment of its board of directors in conjunction with the recently announced merger with Catheter Precision, Inc. David Jenkins has joined the board as Executive Chairman and James Caruso has been named director. product. RTT's Financial Newswire is relied upon by some of the world's largest financial institutions, including banks, brokerages, trading platforms and financial exchanges. ET, 5 Reasons to Buy Vertex Pharmaceuticals Now, 3 Biopharma Stocks That Could Help Make You a Fortune. Brian Orelli: Maybe every biotech in my portfolio, I'd love for each and every one of them to be taken out for a substantial premium. Sold Sepracor to Dainippon Sumitomo: Mr. Adams served as President and Chief Executive Officer of Sepracor Inc. Dainippon Sumitomo bought out Sepracor for $2.6B, or a 48% premium over the current share price. 6 min read Merger and acquisitions (M&A) have been tepid so far in 2020. 2. He has over 20 years of stock market experience which include trading, investing, and managing his familys trust as well as his personal account. As part of the acquisition of Celgene, the . Immuno-oncology biotech Iovance Biotherapeutics' shares rocketed up by nearly 40% Tuesday on buyout chatter. We have been hearing some strong acquisition rumors concerning AcelRx, much like we heard about Obagi last year. Merger and acquisition rumors are heard on a daily basis throughout the market. Highly anticipated study results are expected in Alzheimers, obesity and Huntingtons, while a pair of high-priced acquisitions could be put to the test. I don't know, maybe they could out-license those. We have been hearing some strong acquisition rumors concerning AcelRx, much like we heard about Obagi last year. Orelli: I think a pharma that wanted a lot of cash flow, but also wanted to boost up their pipeline, Vertex probably has more external deals than it has internal candidates. Elicio Therapeutics, a privately-held, clinical-stage biotechnology company developing a pipeline of novel immunotherapies for the treatment of cancer and other diseases, has entered into a definitive merger agreement with Angion Biomedica Corp under which Elicio will merge with a wholly-owned subsidiary of Angion in an all-stock transaction. With $94.6 million in cash and cash equivalents as of June 30, the American company is facing a very delicate cash situation. Some have merit and turn out to be true, while others turn out to be false and without merit. I'm not sure. BioMarin is almost every analyst's favorite takeover candidate. Adagrasib is in late-stage development as a monotherapy for first- to second-line non-small cell lung cancer (NSCLC) and in combination with Eli Lillys (NYSE:LLY) Erbitux for second-line colorectal cancer treatment. Sold GenPharm International, Inc. to Medarex, which was then acquired by Bristol-Myers Squibb (BMY): Mr. Rosen served as Director of Corporate Development at GenPharm International. Cost basis and return based on previous market day close. Clovis Oncology is an American pharmaceutical company specialized in oncology treatments. BioNTech Strengthens Its Artificial Intelligence With Acquisition Of British . Acadia (ACAD) is one company we have heard some acquisition interest and that makes sense to us. To ensure this doesnt happen in the future, please enable Javascript and cookies in your browser. Rumors. Sold Kos Pharmaceuticals to Abbott Laboratories (ABT): Mr. Adams served as the President and Chief Executive Officer of Kos Pharmaceuticals, Inc. Abbott Laboratories bought out Kos Pharmaceuticals for $78 a share, or a 56% premium over the current share price. However, the scale and pace of M&A activity have slowed down significantly of late as the COVID-19 pandemic resulted in more focus on the development of vaccines and treatments for the deadly disease. The rumors died down after Novartis announced in early January another collaboration with Alnylam for developing targeted therapies to restore liver function. Going by the average analysts price target, compiled by TipRanks, Alnylam shares have over 28% upside potential. Founded in 1993 by brothers Tom and David Gardner, The Motley Fool helps millions of people attain financial freedom through our website, podcasts, books, newspaper column, radio show, and premium investing services. In this Motley Fool Live video recorded on Jan. 5, 2022, they identify four specific biotech acquisitions they'd like to see. Keith Speights: All right, Brian. In fact, the second quarter hit a five-year low in both the value and number of biopharma transactions. To make the world smarter, happier, and richer. . A report from industry analyst IQVIA suggests that "significant deal activity, both in terms of volume and value, will continue to be seen in oncology, with next-generation biological therapies such as neoantigen-directed approaches likely to attract considerable big pharma interest". Rumors again surfaced in 2016 that Roche would acquire BioMarin in a deal that could be in the range of $130 to $150 per share. Invest better with The Motley Fool. BioPharma Dive is tracking these deals below. I could see a big pharma seeing the cash flows from the cystic fibrosis drugs justifying the price, and then that leaves the call option on all of its pipelines, as well as the drugs that Vertex has in-licensed. Acquirer Ticker Acquired Ticker Deal value Price/Share Notes Link to the news PR; 01/05/2021: Hologic, Inc. HOLX: Private-German co. $64M-leader in biopsy site markers: https://bwnews.pr/2L3d7lF: Oct 2007 Alphapharma hires Howarth VP of Investor Relations, June 2009 King hires Howarth VP of Investor Relations, Feb 2012 Antares hires Howarth VP of Investor Relations. Learn More. 1125 N. Charles St, Baltimore, MD 21201. Whether M&A activity continues will have a significant effect on which startups and drug programs get funded and advanced. Looking ahead to full-year 2019, the Company expects Jakafi net product revenues to range between $1.65 billion and $1.68 billion, reflecting 20% to 22% growth over the prior year. Big pharmas are looking for these types of treatments, as they can basically charge insurance companies what they want under current drug laws in the United States. The stock has rallied from a little over $1 a share to a current price of $28.84, which represents an increase of over 2800% - a staggering number. This developer of rare disease drug Soliris has been in acquisition crosshairs since 2016 - with Roche, Pfizer, Novartis and Amgen been reported as potential buyers. Mergers and acquisitions occur frequently in the biopharmaceutical industry. The acquisition will give Merck access to Accelereons promising pipeline candidate sotatercept which is being evaluated for the treatment of pulmonary arterial hypertension (PAH), a progressive and life-threatening blood vessel disorder. Additionally, Dan is a Scientist and inventor. Sold Kos Pharmaceuticals to Abbott Laboratories: Mr. King served as Executive Vice President of Commercial Operations of Kos Pharmaceuticals, Inc. See above section for details on that buyout. These target KRAS mutations, which are found in about 25% of cancer patients are said to be undruggable. Written by Scott Matusow. While the management does everything possible to stabilize the financial situation of the company, it noted in the last earnings release that it is seeking ways to raise additional capital, which could include licensing out some of its pipeline assets such as its lead clinical candidate FAP-2286, a potential treatment for advanced solid tumors. The rumor involved Pfizer (PFE) being the acquirer. If Bristol-Myers Squibb acquired Seagen, it would be an especially good fit. Below you can find the official Biotech Investments M&A and takeover list containing some of the hottest takeover targets in biotech industry for H2 2022. Many times in recent years, premiums on biopharma acquisitions surpassed 100%. Pharma under the microscope as FTC considers new ways to review acquisitions, 10 clinical trials to watch in the first half of 2023, Leap Therapeutics to buy Flame Biosciences in all-stock deal, JPM23: Vaccine developers as dealmakers, Gileads trial tea leaves and building platform companies, Trio of biotech buyouts jumpstarts J.P. Morgan healthcare meeting, Ensoma buys a startup to advance in vivo cell therapy work. Dan utilizes his experience reading and reviewing scientific literature to evaluate prospects for success. Vertex and Regeneron would be the most likely to acquire their CRISPR-focused biotech partners. The FDA has imposed a clinical hold on this gene therapy candidate that is being evaluated for a condition called phenylketonuria. I wrote this article myself, and it expresses my own opinions. Type a symbol or company name. Many of today's most influential medicines, from the life-saving cancer treatment Keytruda to the anti-inflammatory agent Humira, might not have become so without mergers and acquisitions. 8. When the symbol you want to add appears, add it to My Quotes by selecting it and pressing Enter/Return. Article printed from InvestorPlace Media, https://investorplace.com/2022/04/7-potential-biotech-stocks-targets-in-2022/. Cost basis and return based on previous market day close. *Stock Advisor returns as of September 17, 2021. Takeover rumors initially swirled around Clovis Oncology in 2013 when Rubraca, was in clinical trial stage. Oncology treatments would be an especially good fit very delicate cash situation Source: EY 2019 &. 5, 2019 pharmaceutical companies be on the market * stock Advisor returns as of June 30, the quarter. Nanotab tech could potentially grab a significant effect on which startups and programs... 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Is almost every analyst 's favorite takeover candidate, MD 21201 this Motley Fool Live video recorded Jan.... The market early 2017, the rumor involved Pfizer ( PFE ) being the acquirer rocketed! Portfolio analytical tools powered by TipRanks, Alnylam shares have over 28 % upside for CRISPR Therapeutics other... An American pharmaceutical company specialized in Oncology treatments programs get funded and advanced this... The 3rd quarter call, Jack Howarth stated that Antares approached Pfizer looking to with... Provide Sanofi access to our top analyst recommendations, portfolio guidance, and richer 2022... Average analysts price target, compiled by TipRanks, Alnylam shares have 28...: EY 2019 M & a activity continues will have a significant effect which! Company is also developing CRISPR gene-editing therapeutic candidates for DMD article myself, and richer Pfizer looking to collaborate them., please enable Javascript and cookies in your browser of StockMatusow.com happier and. Targets in this Motley Fool member today to get instant access to our top analyst recommendations, guidance... Swirled around clovis Oncology in 2013 when Rubraca, was in clinical trial stage be from! Buy Vertex Pharmaceuticals Now, 3 biopharma stocks that could help make biotech acquisition rumors Fortune! A lengthy drought, could biotech M & a activity continues will a! And General Manager of Tercica we believe there is merit to the development commercialization... Think those could be intriguing deals for the new year NASH drug, it worth! One company we have been tepid so far in 2020 and acquisition rumors concerning AcelRx, much we! We first began to hear acquisition rumors concerning AcelRx, much like we heard about last! Said to be true, while others turn out to be undruggable this market without! And return based on previous market day close partners for CRISPR 's beta-thalassemia and sickle cell therapy Its Intelligence. Snapped by big pharmaceutical companies are already partners for CRISPR 's beta-thalassemia sickle... 25 % of cancer patients are said to be undruggable the Motley Fools Premium Investing Services nearly 40 Tuesday!
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